Article
Localization of deletion breakpoints in radiation-induced mutants of the hprt gene in hamster cells.
Mutation research - 1 Oct 1990
Thacker J, Fleck E W, Morris T, Rossiter B J, Morgan T L
Abstract excerpt
DNA was analysed from a large set of hamster hprt gene mutants, some induced by ionising radiations and others occurring naturally, to identify those with large alterations in part of the gene. DNA from these mutants was restricted further with different endonucleases and probed to establish the...
Topics
- Alpha Particles
- Animals
- Blotting, Southern
- Chromosome Deletion
- Chromosome Mapping
- Cricetinae
- Cricetulus
- DNA Probes
- Deoxyribonuclease EcoRI
- Gamma Rays
- Hypoxanthine Phosphoribosyltransferase
- In Vitro Techniques
- Mutation
- Nucleic Acid Hybridization