Article
Low dose-rate X-irradiation induces larger deletions at the human HPRT locus than high dose-rate X-irradiation.
International journal of radiation biology - 1 Nov 1997
Colussi N, Lohman P H
Abstract excerpt
PURPOSE: To investigate the size of deletions induced by low dose-rate (LDR) X-irradiation in relation to the induction by high dose-rate (HDR) X-irradiation at the HPRT locus of human lymphoblastoid WI-L2-NS cells. MATERIALS AND METHODS: The molecular nature of HPRT deletions in human WI-L2-NS l...
Topics
- Cell Line
- Dose-Response Relationship, Radiation
- Gene Deletion
- Humans
- Hypoxanthine Phosphoribosyltransferase
- Mutation
- X-Rays