Article
Low dose-rate X-irradiation induces larger deletions at the human HPRT locus than high dose-rate X-irradiation.
International journal of radiation biology - 1 Nov 1997
Colussi N, Lohman P H
Abstract excerpt
PURPOSE: To investigate the size of deletions induced by low dose-rate (LDR) X-irradiation in relation to the induction by high dose-rate (HDR) X-irradiation at the HPRT locus of human lymphoblastoid WI-L2-NS cells. MATERIALS AND METHODS: The molecular nature of HPRT deletions in human WI-L2-NS lymphoblasts was investigated after LDR or HDR X-irradiation with a total dose of 4 Gy using a set of nine Xq26 sequence...
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