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Article

PON1 status does not influence cholinesterase activity in Egyptian agricultural workers exposed to chlorpyrifos.

Toxicology and applied pharmacology - 15 Dec 2012

Ellison Corie A, Crane Alice L, Bonner Matthew R, Knaak James B, Browne Richard W, Lein Pamela J, Olson James R

Abstract excerpt

Animal studies have shown that paraoxonase 1 (PON1) genotype can influence susceptibility to the organophosphorus pesticide chlorpyrifos (CPF). However, Monte Carlo analysis suggests that PON1 genotype may not affect CPF-related toxicity at low exposure conditions in humans. The current study sought to determine the influence of PON1 genotype on the activity of blood cholinesterase as well as the effect of CPF...

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Source

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Identifiers

PMID: 22975224
DOI: 10.1016/j.taap.2012.08.031
PMCID: PMC3513664

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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PON1 status does not influence cholinesterase activity in Egyptian agricultural workers exposed to chlorpyrifos.PMID 22975224Read ↗

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