Article
Paraoxonase 1 and its relationship with pesticide biomarkers in indigenous Mexican farmworkers.
Journal of occupational and environmental medicine - 1 Mar 2014
Bernal-Hernández Yael Yvette, Medina-Díaz Irma Martha, Barrón-Vivanco Briscia Socorro, Robledo-Marenco María de Lourdes, Girón-Pérez Manuel Iván, Pérez-Herrera Norma Elena, Quintanilla-Vega Betzabet, Cerda-Flores Ricardo, Rojas-García Aurora Elizabeth
Abstract excerpt
OBJECTIVE: Biomarkers of pesticide toxicity and paraoxonase 1 (PON1) phenotype and genotypes were evaluated in indigenous Mexican farmworkers exposed mainly to organophosphate (OP) pesticides. METHODS: Acetylcholinesterase, butyrylcholinesterase, and PON1 activities--arylesterase and CMPAase activities--were evaluated spectrophotometrically. PON1 55 and 192 polymorphisms were determined by real-time polymerase...
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