Article
Role of arginine 29 and glutamic acid 81 interactions in the conformational stability of human chloride intracellular channel 1.
Biochemistry - 9 Oct 2012
Legg-E'silva Derryn, Achilonu Ikechukwu, Fanucchi Sylvia, Stoychev Stoyan, Fernandes Manuel, Dirr Heini W
Abstract excerpt
The ion channel protein CLIC1 exists in both a soluble conformation in the cytoplasm and a membrane-bound conformation. The conformational stability of soluble CLIC1 demonstrates pH sensitivity which may be attributable to very specific residues that function as pH sensors. These sensors could be...
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