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Article

Helix O modulates voltage dependency of CLC-1.

Pflugers Archiv : European journal of physiology - 1 Feb 2017

Seong Ju Yong, Ha Kotdaji, Hong Chansik, Myeong Jongyun, Lim Hyun-Ho, Yang Dongki, So Insuk

Abstract excerpt

The chloride channel (CLC) family of proteins consists of channels and transporters that share similarities in architecture and play essential roles in physiological functions. Among the CLC family, CLC-1 channels have the representative homodimeric double-barreled structure carrying two gating processes. One is protopore gating that acts on each pore independently by glutamate residue (Eext). The other is common...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27921211
DOI: 10.1007/s00424-016-1907-5

Genes

CLC

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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