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Article

Ionic currents mediated by a prokaryotic homologue of CLC Cl- channels.

The Journal of general physiology - 1 Feb 2004

Accardi Alessio, Kolmakova-Partensky Ludmila, Williams Carole, Miller Christopher

Abstract excerpt

CLC-ec1 is an E. coli homologue of the CLC family of Cl- channels, which are widespread throughout eukaryotic organisms. The structure of this membrane protein is known, and its physiological role has been described, but our knowledge of its functional characteristics is severely limited by the absence of electrophysiological recordings. High-density reconstitution and incorporation of crystallization-quality...

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Identifiers

PMID: 14718478
DOI: 10.1085/jgp.200308935
PMCID: PMC2217429

Genes

CLC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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