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Article

The methyltransferase adaptor protein Trm112 is involved in biogenesis of both ribosomal subunits.

Molecular biology of the cell - 1 Nov 2012

Sardana Richa, Johnson Arlen W

Abstract excerpt

We previously identified Bud23 as the methyltransferase that methylates G1575 of rRNA in the P-site of the small (40S) ribosomal subunit. In this paper, we show that Bud23 requires the methyltransferase adaptor protein Trm112 for stability in vivo. Deletion of Trm112 results in a bud23Δ-like mutant phenotype. Thus Trm112 is required for efficient small-subunit biogenesis. Genetic analysis suggests the slow growth...

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Identifiers

PMID: 22956767
DOI: 10.1091/mbc.E12-05-0370
PMCID: PMC3484107

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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