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Article

Bud23 promotes the final disassembly of the small subunit Processome in Saccharomyces cerevisiae.

PLoS genetics - 1 Dec 2020

Black Joshua J, Sardana Richa, Elmir Ezzeddine W, Johnson Arlen W

Abstract excerpt

The first metastable assembly intermediate of the eukaryotic ribosomal small subunit (SSU) is the SSU Processome, a large complex of RNA and protein factors that is thought to represent an early checkpoint in the assembly pathway. Transition of the SSU Processome towards continued maturation requires the removal of the U3 snoRNA and biogenesis factors as well as ribosomal RNA processing. While the factors that...

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Source

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Identifiers

PMID: 33306676
DOI: 10.1371/journal.pgen.1009215
PMCID: PMC7758049

Genes

BMS1
IMP4
NOP14

Provenance

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Bud23 promotes the final disassembly of the small subunit Processome in Saccharomyces cerevisiae.PMID 33306676Read ↗

The rRNA methyltransferase Bud23 shows functional interaction with components of the SSU processome and RNase MRP.Semantic proximity Read ↗

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Utp14 interaction with the small subunit processome.Semantic proximity Read ↗

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Utp14 Recruits and Activates the RNA Helicase Dhr1 To Undock U3 snoRNA from the Preribosome.Semantic proximity Read ↗

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hUTP24 is essential for processing of the human rRNA precursor at site A1, but not at site A0.Semantic proximity Read ↗

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