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Article

Spb1p-directed formation of Gm2922 in the ribosome catalytic center occurs at a late processing stage.

Molecular cell - 19 Nov 2004

Lapeyre Bruno, Purushothaman Suresh K

Abstract excerpt

rRNA molecules undergo extensive posttranscriptional modification, predominantly 2'-O-ribose methylation and pseudouridine formation, both of which are guided by the numerous small nucleolar RNAs in eukaryotes. Here, we describe an exception to this rule. The essential yeast nucleolar protein Spb1p is a site-specific rRNA methyltransferase modifying the universally conserved G2922 that is located within the A...

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Identifiers

PMID: 15546625
DOI: 10.1016/j.molcel.2004.10.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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