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Article

Yeast Rrp8p, a novel methyltransferase responsible for m1A 645 base modification of 25S rRNA.

Nucleic acids research - 1 Jan 2013

Peifer Christian, Sharma Sunny, Watzinger Peter, Lamberth Stefanie, Kötter Peter, Entian Karl-Dieter

Abstract excerpt

Ribosomal RNA undergoes various modifications to optimize ribosomal structure and expand the topological potential of RNA. The most common nucleotide modifications in ribosomal RNA (rRNA) are pseudouridylations and 2'-O methylations (Nm), performed by H/ACA box snoRNAs and C/D box snoRNAs, respectively. Furthermore, rRNAs of both ribosomal subunits also contain various base modifications, which are catalysed by...

Topics

Adenine
Methylation
Methyltransferases
Mutation
Nuclear Proteins
Protein O-Methyltransferase
RNA, Ribosomal
Ribonucleoproteins, Small Nucleolar
Ribosome Subunits, Large, Eukaryotic
S-Adenosylmethionine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Saccharomyces cerevisiae Proteins

Sequence Deletion

Source

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Identifiers

PMID: 23180764
DOI: 10.1093/nar/gks1102
PMCID: PMC3553958

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Yeast Rrp8p, a novel methyltransferase responsible for m1A 645 base modification of 25S rRNA.PMID 23180764Read ↗

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