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Article

A methyltransferase-independent function for Rmt3 in ribosomal subunit homeostasis.

The Journal of biological chemistry - 29 May 2009

Perreault Audrey, Gascon Suzanne, D'Amours Annie, Aletta John M, Bachand Francois

Abstract excerpt

Schizosaccharomyces pombe Rmt3 is a member of the protein-arginine methyltransferase (PRMT) family and is the homolog of human PRMT3. We previously characterized Rmt3 as a ribosomal protein methyltransferase based on the identification of the 40 S Rps2 (ribosomal protein S2) as a substrate of Rmt3. RMT3-null cells produce nonmethylated Rps2 and show mis-regulation of the 40 S/60 S ribosomal subunit ratio due to a...

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Identifiers

PMID: 19359250
DOI: 10.1074/jbc.M109.004812
PMCID: PMC2685685

Genes

PRMT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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