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Article

The rRNA methyltransferase Bud23 shows functional interaction with components of the SSU processome and RNase MRP.

RNA (New York, N.Y.) - 1 Jun 2013

Sardana Richa, White Joshua P, Johnson Arlen W

Abstract excerpt

Bud23 is responsible for the conserved methylation of G1575 of 18S rRNA, in the P-site of the small subunit of the ribosome. bud23Δ mutants have severely reduced small subunit levels and show a general failure in cleavage at site A2 during rRNA processing. Site A2 is the primary cleavage site for separating the precursors of 18S and 25S rRNAs. Here, we have taken a genetic approach to identify the functional...

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Source

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Identifiers

PMID: 23604635
DOI: 10.1261/rna.037671.112
PMCID: PMC3683916

Genes

BUD23

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

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The rRNA methyltransferase Bud23 shows functional interaction with components of the SSU processome and RNase MRP.PMID 23604635Read ↗

Bud23 promotes the final disassembly of the small subunit Processome in Saccharomyces cerevisiae.Semantic proximity Read ↗

The methyltransferase adaptor protein Trm112 is involved in biogenesis of both ribosomal subunits.Semantic proximity Read ↗

Bud23 methylates G1575 of 18S rRNA and is required for efficient nuclear export of pre-40S subunits.Semantic proximity Read ↗

Physical and functional interaction between the methyltransferase Bud23 and the essential DEAH-box RNA helicase Ecm16.Semantic proximity Read ↗

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