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Article

A case-parent triad assessment of folate metabolic genes and the risk of childhood acute lymphoblastic leukemia.

Cancer causes & control : CCC - 1 Nov 2012

Lupo Philip J, Nousome Darryl, Kamdar Kala Y, Okcu M Fatih, Scheurer Michael E

Abstract excerpt

PURPOSE: We conducted a case-parent triad study evaluating the role of maternal and offspring genotypes in the folate metabolic pathway on childhood acute lymphoblastic leukemia (ALL) risk. METHODS: Childhood ALL case-parent triads (n = 120) were recruited from Texas Children's Hospital. DNA samples were genotyped using the Sequenom iPLEX MassARRAY for 68 tagSNPs in six folate metabolic pathway genes (MTHFR,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22941668
DOI: 10.1007/s10552-012-0058-z
PMCID: PMC3472623

Genes

BHMT
MTR
TYMS
DHFR
MTHFR
MTRR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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