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Article

Polymorphisms in folate-related genes: impact on risk of adult acute lymphoblastic leukemia rather than pediatric in Han Chinese.

Leukemia & lymphoma - 1 Sept 2011

Yang Lin, Liu Liang, Wang Jianxiang, Qiu Lugui, Mi Yingchang, Ma Xiaotang, Xiao Zhijian

Abstract excerpt

Folate metabolism plays an essential role in the processes of DNA synthesis and methylation. An aberrant folate metabolism caused by a genetic polymorphism may lead to genomic instability and affect the susceptibility to malignancies including acute lymphoblastic leukemia (ALL). This study was designed to explore the correlation between the polymorphisms in folate-related genes and the risk of ALL in Han Chinese....

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Source

Identifiers

PMID: 21657963
DOI: 10.3109/10428194.2011.578186

Genes

ABCG2
MTHFR
MTRR
RFC1
DHFR
MTHFD1
MTR
SHMT1
TYMS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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