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Article

Folate related gene polymorphisms and susceptibility to develop childhood acute lymphoblastic leukaemia.

British journal of haematology - 1 Jan 2010

Koppen Ilan J N, Hermans Frederik J R, Kaspers Gertjan J L

Abstract excerpt

Acute lymphoblastic leukaemia (ALL) is the most common paediatric cancer, accounting for nearly 30% of all paediatric cancers and 80% of childhood leukaemias. Polymorphisms in folate-related genes may influence the susceptibility to childhood ALL. This review summarizes the results of 14 studies that focussed on the relationship between folate-related gene polymorphisms and the susceptibility to ALL and that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Predisposition to Disease

Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Source

Identifiers

PMID: 19775302
DOI: 10.1111/j.1365-2141.2009.07898.x

Genes

MTHFR
MTR
MTRR
NNMT
RFC1
SHMT1
SLC19A1
TYMS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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