Article
Using a Bayesian hierarchical model for identifying single nucleotide polymorphisms associated with childhood acute lymphoblastic leukemia risk in case-parent triads.
PloS one - 1 Jan 2013
Cao Ying, Lupo Philip J, Swartz Michael D, Nousome Darryl, Scheurer Michael E
Abstract excerpt
Childhood acute lymphoblastic leukemia (ALL) is a condition that arises from complex etiologies. The absence of consistent environmental risk factors and the presence of modest familial associations suggest ALL is a complex trait with an underlying genetic component. The identification of genetic factors associated with disease is complicated by complex genetic covariance structures and multiple testing issues....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.