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Article

AKT1 fails to replicate as a longevity-associated gene in Danish and German nonagenarians and centenarians.

European journal of human genetics : EJHG - 1 May 2013

Nygaard Marianne, Soerensen Mette, Flachsbart Friederike, Mengel-From Jonas, Tan Qihua, Schreiber Stefan, Nebel Almut, Christensen Kaare, Christiansen Lene

Abstract excerpt

In addition to APOE and FOXO3, AKT1 has recently been suggested as a third consistent longevity gene, with variants in AKT1 found to be associated with human lifespan in two previous studies. Here, we evaluated AKT1 as a longevity-associated gene across populations by attempting to replicate the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins c-akt

Source

Open in PubMed Open full text

Identifiers

PMID: 22929028
DOI: 10.1038/ejhg.2012.196
PMCID: PMC3641374

Genes

AKT1
APOE
FOXO3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22929028-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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