Article
Absence of significant associations between four AKT1 SNP markers and schizophrenia in the Taiwanese population.
Psychiatric genetics - 1 Feb 2006
Liu Yu-Li, Fann Cathy Shen-Jang, Liu Chih-Min, Wu Jer-Yuarn, Hung Shuen-Iu, Chan Hung-Yu, Chen Jiahn-Jyh, Pan Chia-Ching, Liu Shih-Kai, Hsieh Ming H, Hwang Tzung-Jeng, Ouyang Wen-Chen, Chen Chun-Ying, Lin Jin-Jia, Chou Frank Huang-Chih, Chueh Ching-Mo, Liu Wei-Ming, Tsuang Ming-Ming, Faraone Stephen V, Tsuang Ming T, Chen Wei J, Hwu Hai-Gwo
Abstract excerpt
AKT1 (V-akt murine thymoma viral oncogene homolog 1) is a protein kinase isoform of AKT. Five single-nucleotide polymorphisms, rs3803300, rs1130214, rs3730358, rs2498799 and rs2494732, at the genomic region of AKT1 have been reported to be significantly associated with schizophrenia. We tested for the presence of these five single-nucleotide polymorphisms in a Taiwanese population by genotyping 218 co-affected...