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Article

Variation in Akt protein kinases in human populations.

American journal of physiology. Regulatory, integrative and comparative physiology - 1 Dec 2017

Rotwein Peter

Abstract excerpt

The three Akt kinases are related proteins that are essential for normal growth and metabolic regulation and are implicated as key signaling mediators in many physiological and pathophysiological processes. Each Akt is activated by common biochemical signals that act downstream of growth factor and hormone receptors via phosphatidylinositol-3 kinase, and each controls several downstream pathways. The importance...

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Source

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Identifiers

PMID: 28931550
DOI: 10.1152/ajpregu.00295.2017
PMCID: PMC5814693

Genes

AKT2
AKT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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