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Article

Developmental dynamics of post-selection thymic DN iNKT.

PloS one - 1 Jan 2012

Yassai Maryam, Cooley Brian, Gorski Jack

Abstract excerpt

BACKGROUND: Invariant natural killer T (iNKT) cells develop in the thymus and branch off from the maturation pathway of conventional T cell at the DP stage. While different stages of iNKT cellular development have been defined, the actual time that iNKT cell precursors spend at each stage is still unknown. METHODOLOGY/PRINCIPAL FINDING: Here we report on maturation dynamics of post-selection DN iNKT cells by...

Topics

Animals
CD4-Positive T-Lymphocytes
CD8-Positive T-Lymphocytes
Hyaluronan Receptors
Injections
Mice
Natural Killer T-Cells
Phenotype
Receptors, Antigen, T-Cell, alpha-beta
Spleen
Thymocytes
Thymus Gland

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22927977
DOI: 10.1371/journal.pone.0043509
PMCID: PMC3425480

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