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Article

Phenotypic and functional stages in the intrathymic development of alpha beta T cells.

Immunology today - 1 Feb 1991

Nikolić-Zugić J

Abstract excerpt

The thymus is the main site of T-cell maturation. On arrival in the thymus, CD8-CD4- double-negative (DN) T-cell precursors undergo extensive gene rearrangement, phenotypic alteration and biochemical modification to yield the population of thymocytes that undergoes intrathymic selection. The selected mature thymocytes then go on to seed the periphery. In this article Janko Nikolić-Zugić discusses the labyrinthine...

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Identifiers

PMID: 2059306
DOI: 10.1016/0167-5699(91)90160-u

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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