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Article

Targeted manipulation of heterochromatin rescues MeCP2 Rett mutants and re-establishes higher order chromatin organization.

Nucleic acids research - 1 Dec 2012

Casas-Delucchi Corella S, Becker Annette, Bolius Janine J, Cardoso M Cristina

Abstract excerpt

Heterochromatic regions represent a significant portion of the mammalian genome and have been implied in several important cellular processes, including cell division and genomic stability. However, its composition and dynamics remain largely unknown. To better understand how heterochromatin functions and how it is organized within the context of the cell nucleus, we have developed molecular tools allowing the...

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Identifiers

PMID: 22923521
DOI: 10.1093/nar/gks784
PMCID: PMC3526307

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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