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Article

ATRX Contributes to MeCP2-Mediated Pericentric Heterochromatin Organization during Neural Differentiation.

International journal of molecular sciences - 29 Oct 2019

Marano Domenico, Fioriniello Salvatore, Fiorillo Francesca, Gibbons Richard J, D'Esposito Maurizio, Della Ragione Floriana

Abstract excerpt

Methyl-CpG binding protein 2 (MeCP2) is a multi-function factor involved in locus-specific transcriptional modulation and the regulation of genome architecture, e.g., pericentric heterochromatin (PCH) organization. MECP2 mutations are responsible for Rett syndrome (RTT), a devastating postnatal neurodevelopmental disorder, the pathogenetic mechanisms of which are still unknown. MeCP2, together with...

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Source

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Identifiers

PMID: 31671722
DOI: 10.3390/ijms20215371
PMCID: PMC6862095

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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