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Article

MeCP2-chromatin interactions include the formation of chromatosome-like structures and are altered in mutations causing Rett syndrome.

The Journal of biological chemistry - 21 Sept 2007

Nikitina Tatiana, Ghosh Rajarshi P, Horowitz-Scherer Rachel A, Hansen Jeffrey C, Grigoryev Sergei A, Woodcock Christopher L

Abstract excerpt

hMeCP2 (human methylated DNA-binding protein 2), mutations of which cause most cases of Rett syndrome (RTT), is involved in the transmission of repressive epigenetic signals encoded by DNA methylation. The present work focuses on the modifications of chromatin architecture induced by MeCP2 and th...

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Source

Identifiers

PMID: 17660293
DOI: 10.1074/jbc.M704304200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17660293-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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