Article
Variants in CXADR and F2RL1 are associated with blood pressure and obesity in African-Americans in regions identified through admixture mapping.
Journal of hypertension - 1 Oct 2012
Shetty Priya B, Tang Hua, Tayo Bamidele O, Morrison Alanna C, Hanis Craig L, Rao Dabeeru C, Young Jeffery H, Fox Ervin R, Boerwinkle Eric, Cooper Richard S, Risch Neil J, Zhu Xiaofeng
Abstract excerpt
OBJECTIVE: Genetic variants in 296 genes in regions identified through admixture mapping of hypertension, BMI, and lipids were assessed for association with hypertension, blood pressure (BP), BMI, and high-density lipoprotein cholesterol (HDL-C). METHODS: This study identified coding SNPs identified from HapMap2 data that were located in genes on chromosomes 5, 6, 8, and 21, wherein ancestry association evidence...
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