Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Admixture mapping identifies genetic regions associated with blood pressure phenotypes in African Americans.

PloS one - 1 Jan 2020

Liu Zhi, Shriner Daniel, Hansen Nancy F, Rotimi Charles N, Mullikin James C

Abstract excerpt

Hypertension occurs at a higher rate in African Americans than in European Americans. Based on the assumption that causal variants are more frequently found on DNA segments inherited from the ancestral population with higher disease risk, we employed admixture mapping to identify genetic loci with excess local African ancestry associated with blood pressure. Chromosomal regions 1q21.2-21.3, 4p15.1, 19q12 and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Black or African American
Share to Blood Pressure

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosome Mapping

Share to Genetic Loci

Share to Genome-Wide Association Study

Share to Polymorphism, Single Nucleotide

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 32315356
DOI: 10.1371/journal.pone.0232048
PMCID: PMC7173845

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Admixture mapping identifies genetic regions associated with blood pressure phenotypes in African Americans.PMID 32315356Read ↗

Admixture mapping in the Hispanic Community Health Study/Study of Latinos reveals regions of genetic associations with blood pressure traits.Semantic proximity Read ↗

A high-density admixture scan in 1,670 African Americans with hypertension.Semantic proximity Read ↗

Admixture mapping provides evidence of association of the VNN1 gene with hypertension.Semantic proximity Read ↗

Admixture mapping for hypertension loci with genome-scan markers.Semantic proximity Read ↗

Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study.Semantic proximity Read ↗

Combined admixture mapping and association analysis identifies a novel blood pressure genetic locus on 5p13: contributions from the CARe consortium.Semantic proximity Read ↗

Admixture mapping of serum vitamin D and parathyroid hormone concentrations in the African American-Diabetes Heart Study.Semantic proximity Read ↗

Admixture mapping of ankle-arm index: identification of a candidate locus associated with peripheral arterial disease.Semantic proximity Read ↗

Variants in CXADR and F2RL1 are associated with blood pressure and obesity in African-Americans in regions identified through admixture mapping.Semantic proximity Read ↗

Rare coding variants associated with blood pressure variation in 15 914 individuals of African ancestry.Semantic proximity Read ↗

Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.Semantic proximity Read ↗

Admixture mapping comes of age.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.