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Article

Replication of European hypertension associations in a case-control study of 9,534 African Americans.

PloS one - 1 Jan 2021

Kaur Harpreet, Crawford Dana C, Liang Jingjing, Benchek Penelope, Zhu Xiaofeng, Kallianpur Asha R, Bush William S

Abstract excerpt

OBJECTIVE: Hypertension is more prevalent in African Americans (AA) than other ethnic groups. Genome-wide association studies (GWAS) have identified loci associated with hypertension and other cardio-metabolic traits like type 2 diabetes, coronary artery disease, and body mass index (BMI), however the AA population is underrepresented in these studies. In this study, we examined a large AA cohort for the...

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PMID: 34793544
DOI: 10.1371/journal.pone.0259962
PMCID: PMC8601554

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