Article
Repair of O4-alkylthymine damage in human cells.
Basic life sciences - 1 Jan 1990
Wani A A, Wani G, D'Ambrosio S M
Abstract excerpt
The capacity of a cell to repair damage is the first step in preventing the deleterious consequences of DNA structural alterations induced by the exposure to mutagenic carcinogens. Mammalian cells, having complex genetic organization, have evolved sophisticated mechanisms for the maintenance of i...
Topics
- Alkylating Agents
- Alkylation
- Cell Transformation, Neoplastic
- DNA
- DNA Damage
- DNA Repair
- Humans
- Mutation
- Neoplasms
- Thymine