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Article

Modulation of ethylnitrosourea-induced toxicity and mutagenicity in human cells by O6-benzylguanine.

Cancer research - 15 Jul 1992

Bronstein S M, Hooth M J, Swenberg J A, Skopek T R

Abstract excerpt

We have examined the contributions of O6-alkylguanine-DNA alkyl-transferase (AGT) and nucleotide excision repair to the protection of human cells from the toxic and mutagenic effects of ethylnitrosourea. Three human lymphoblastoid cell lines were used: one which possesses both of these DNA repair...

Topics

Alkylation
Cell Line, Transformed
Cell Survival
DNA Repair
Ethylnitrosourea
Guanine
Humans
Lymphocytes
Methyltransferases
Mutation
O(6)-Methylguanine-DNA Methyltransferase
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1617659

Genes

AGT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1617659-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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