Article
Developmental delays and reduced pup ultrasonic vocalizations but normal sociability in mice lacking the postsynaptic cell adhesion protein neuroligin2.
Behavioural brain research - 15 Aug 2013
Wöhr Markus, Silverman Jill L, Scattoni Maria L, Turner Sarah M, Harris Mark J, Saxena Roheeni, Crawley Jacqueline N
Abstract excerpt
Mutations in neurexin and neuroligin genes have been associated with neurodevelopmental disabilities including autism. Autism spectrum disorder is diagnosed by aberrant reciprocal social interactions, deficits in social communication, and repetitive, stereotyped patterns of behaviors, along with narrow restricted interests. Mouse models have been successfully used to study physiological and behavioral outcomes of...
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