Article
Absence of deficits in social behaviors and ultrasonic vocalizations in later generations of mice lacking neuroligin4.
Genes, brain, and behavior - 1 Nov 2012
Ey E, Yang M, Katz A M, Woldeyohannes L, Silverman J L, Leblond C S, Faure P, Torquet N, Le Sourd A-M, Bourgeron T, Crawley J N
Abstract excerpt
Mutations in NLGN4X have been identified in individuals with autism spectrum disorders and other neurodevelopmental disorders. A previous study reported that adult male mice lacking neuroligin4 (Nlgn4) displayed social approach deficits in the three-chambered test, altered aggressive behaviors and reduced ultrasonic vocalizations. To replicate and extend these findings, independent comprehensive analyses of...
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