Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neuroligin‐3‐deficient mice: model of a monogenic heritable form of autism with an olfactory deficit

19 Feb 2009

Abstract excerpt

Autism spectrum disorder (ASD) is a frequent neurodevelopmental disorder characterized by variable clinical severity. Core symptoms are qualitatively impaired communication and social behavior, highly restricted interests and repetitive behaviors. Although recent work on genetic mutations in ASD has shed light on the pathophysiology of the disease, classifying it essentially as a synaptopathy, no treatments are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Genetics and Reproduction
Share to Autism Spectrum Disorder Research
Share to Virology and Viral Diseases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19243448
DOI: 10.1111/j.1601-183x.2009.00487.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 17 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neuroligin‐3‐deficient mice: model of a monogenic heritable form of autism with an olfactory deficitPMID 19243448Read ↗

Minimal aberrant behavioral phenotypes of neuroligin-3 R451C knockin mice.Semantic proximity Read ↗

Unraveling the Role of Neuroligin3 in Autism Spectrum Disorders: Pathophysiological Insights and Targeted Therapies.Semantic proximity Read ↗

Development of an autism severity score for mice using Nlgn4 null mutants as a construct-valid model of heritable monogenic autism.Semantic proximity Read ↗

Environmental enrichment modulates affiliative and aggressive social behaviour in the neuroligin-3 R451C mouse model of autism spectrum disorder.Semantic proximity Read ↗

A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice.Semantic proximity Read ↗

Developmental delays and reduced pup ultrasonic vocalizations but normal sociability in mice lacking the postsynaptic cell adhesion protein neuroligin2.Semantic proximity Read ↗

High resolution magnetic resonance imaging for characterization of the neuroligin-3 knock-in mouse model associated with autism spectrum disorder.Semantic proximity Read ↗

Juvenile manifestation of ultrasound communication deficits in the neuroligin-4 null mutant mouse model of autism.Semantic proximity Read ↗

Analyses of the Autism-associated Neuroligin-3 R451C Mutation in Human Neurons Reveals a Gain-of-Function Synaptic MechanismSemantic proximity Read ↗

Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice.Semantic proximity Read ↗

Developmental plasticity shapes synaptic phenotypes of autism-associated neuroligin-3 mutations in the calyx of Held.Semantic proximity Read ↗

A review on the current neuroligin mouse models.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.