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Article

Copper modulates the phenotypic response of activated BV2 microglia through the release of nitric oxide.

Nitric oxide : biology and chemistry - 1 Dec 2012

Rossi-George Alba, Guo Chang-Jiang, Oakes Benjamin L, Gow Andrew J

Abstract excerpt

Microglia are resident immune cells of the central nervous system. Their persistent activation in neurodegenerative diseases, traditionally attributed to neuronal dysfunction, may be due to a microglial failure to modulate the release of cytotoxic mediators such as nitric oxide (NO). The persistent activation of microglia with the subsequent release of NO vis-á-vis the accumulation of redox transition metals such...

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Identifiers

PMID: 22819698
DOI: 10.1016/j.niox.2012.07.002
PMCID: PMC3731386

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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