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Article

Phenotype and secretory responses to oxidative stress in microglia.

Developmental neuroscience - 1 Jan 2013

Pathipati Praneeti, Müller Sebastian, Jiang Xiangning, Ferriero Donna

Abstract excerpt

The neonatal brain is particularly susceptible to oxidative stress. Our group has previously shown that following hypoxic-ischemic injury, hydrogen peroxide (H2O2) levels rise significantly particularly in the neonatal brain and are sustained for up to 7 days. This rapidly accumulated H2O2 is detrimental in the iron-rich immature brain as it can lead to the generation of dangerous free radicals that can cause...

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PMID: 23548608
DOI: 10.1159/000346159

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MIP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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