Article
[Effect of Fasudil on the phenotype conversion of LPS-stimulated BV-2 microglia].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology - 1 Aug 2012
Zhang Hai-fei, Guo Min-fang, Meng Jian, Liu Chun-yun, Li Yan-hua, Yu Jie-zhong, Hou Shao-wei, Feng Ling, Xiao Bao-guo, Ma Cun-gen
Abstract excerpt
AIM: To explore the effect of Fasudil on LPS-stimulated BV-2 microglia in inflammatory reaction and phenotype conversion. METHODS: The routinely cultured BV-2 microglia in vitro were divided into PBS control group, PBS plus Fasudil treatment group, LPS stimulation group and LPS plus Fasudil group. We determined the production of NO by Griess reaction, the level of TNF-α by ELISA, and analyzed the M1 and M2...
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