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Article

Prolonged lipopolysaccharide exposure induces transient immunosuppression in BV2 microglia.

Journal of cellular physiology - 1 Feb 2019

Twayana Krishna Sundar, Chaudhari Namrata, Ravanan Palaniyandi

Abstract excerpt

Continuous pre-exposure of immune cells to low level of inflammatory stimuli makes them hyporesponsive to subsequent exposure. This pathophysiological adaptation; known as endotoxin tolerance is a general paradigm behind several disease pathogenesis. Current study deals with this immunosuppression with respect to BV2 microglia. We attempted to investigate their immune response under prolonged endotoxin exposure...

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Identifiers

PMID: 30054903
DOI: 10.1002/jcp.27064

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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