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Article

Reduced inflammatory phenotype in microglia derived from neonatal rat spinal cord versus brain.

PloS one - 1 Jan 2014

Baskar Jesudasan Sam Joshva, Todd Kathryn G, Winship Ian R

Abstract excerpt

Microglia are the primary immune cells of the central nervous system (CNS). Membrane bound sensors on their processes monitor the extracellular environment and respond to perturbations of the CNS such as injury or infection. Once activated, microglia play a crucial role in determining neuronal survival. Recent studies suggest that microglial functional response properties vary across different regions of the CNS....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24914808
DOI: 10.1371/journal.pone.0099443
PMCID: PMC4051776

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