Article
Anthocyanin effects on microglia M1/M2 phenotype: Consequence on neuronal fractalkine expression.
Behavioural brain research - 15 May 2016
Meireles Manuela, Marques Cláudia, Norberto Sónia, Santos Paulo, Fernandes Iva, Mateus Nuno, Faria Ana, Calhau Conceição
Abstract excerpt
Microglia mediate multiple aspects of neuroinflammation, including cytotoxicity, repair, regeneration, and immunosuppression due to their ability to acquire diverse activation states, or phenotypes. Modulation of microglial phenotype or microglia-neuron crosstalk can be an appealing neurotherapeutic strategy. Anthocyanins are a class of flavonoids found e.g., in berries that has been attracting interest due to...
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