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Article

Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro.

Brain, behavior, and immunity - 1 Aug 2013

Chhor Vibol, Le Charpentier Tifenn, Lebon Sophie, Oré Marie-Virgine, Celador Idoia Lara, Josserand Julien, Degos Vincent, Jacotot Etienne, Hagberg Henrik, Sävman Karin, Mallard Carina, Gressens Pierre, Fleiss Bobbi

Abstract excerpt

Microglia mediate multiple facets of neuroinflammation, including cytotoxicity, repair, regeneration, and immunosuppression due to their ability to acquire diverse activation states, or phenotypes. Modulation of microglial phenotype is an appealing neurotherapeutic strategy but a comprehensive study of classical and more novel microglial phenotypic markers in vitro is lacking. The aim of this study was to outline...

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Identifiers

PMID: 23454862
DOI: 10.1016/j.bbi.2013.02.005
PMCID: PMC3694309

Genes

SOCS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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