Article
Risk variants for psoriasis vulgaris in a large case-control collection and association with clinical subphenotypes.
Human molecular genetics - 15 Oct 2012
Julià Antonio, Tortosa Raül, Hernanz José Manuel, Cañete Juan D, Fonseca Eduardo, Ferrándiz Carlos, Unamuno Pablo, Puig Lluís, Fernández-Sueiro José Luís, Sanmartí Raimon, Rodríguez Jesús, Gratacós Jordi, Dauden Esteban, Sánchez-Carazo José Luís, López-Estebaranz José Luís, Moreno-Ramírez David, Queiró Rubén, Montilla Carlos, Torre-Alonso Juan Carlos, Pérez-Venegas José Javier, Vanaclocha Francisco, Herrera Enrique, Muñoz-Fernández Santiago, González Carlos, Roig Daniel, Erra Alba, Acosta Isabel, Fernández-Nebro Antonio, Zarco Pedro, Alonso Arnald, López-Lasanta María, García-Montero Andrés, Gelpí Josep Lluís, Absher Devin, Marsal Sara
Abstract excerpt
Recent genome-wide association studies (GWASs) have identified >20 new loci associated with the susceptibility to psoriasis vulgaris (PsV) risk. We investigated the association of PsV and its main clinical subphenotypes with 32 loci having previous genome-wide evidence of association with PsV (P < 5e-8) or strong GWAS evidence (P < 5e-5 in discovery and P < 0.05 in replication sample) in a large cohort of PsV...
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