Article
A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci.
PLoS genetics - 28 Mar 2008
Liu Ying, Helms Cynthia, Liao Wilson, Zaba Lisa C, Duan Shenghui, Gardner Jennifer, Wise Carol, Miner Andrew, Malloy M J, Pullinger Clive R, Kane John P, Saccone Scott, Worthington Jane, Bruce Ian, Kwok Pui-Yan, Menter Alan, Krueger James, Barton Anne, Saccone Nancy L, Bowcock Anne M
Abstract excerpt
A genome-wide association study was performed to identify genetic factors involved in susceptibility to psoriasis (PS) and psoriatic arthritis (PSA), inflammatory diseases of the skin and joints in humans. 223 PS cases (including 91 with PSA) were genotyped with 311,398 single nucleotide polymorphisms (SNPs), and results were compared with those from 519 Northern European controls. Replications were performed...
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