Article
Variants at HLA-A, HLA-C, and HLA-DQB1 Confer Risk of Psoriasis Vulgaris in Japanese.
The Journal of investigative dermatology - 1 Mar 2018
Hirata Jun, Hirota Tomomitsu, Ozeki Takeshi, Kanai Masahiro, Sudo Takeaki, Tanaka Toshihiro, Hizawa Nobuyuki, Nakagawa Hidemi, Sato Shinichi, Mushiroda Taisei, Saeki Hidehisa, Tamari Mayumi, Okada Yukinori
Abstract excerpt
Psoriasis vulgaris (PsV) is an autoimmune disease of skin and joints with heterogeneity in epidemiologic and genetic landscapes of global populations. We conducted an initial genome-wide association study and a replication study of PsV in the Japanese population (606 PsV cases and 2,052 controls). We identified significant associations of the single nucleotide polymorphisms with PsV risk at TNFAIP3-interacting...
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