Fine mapping major histocompatibility complex associations in psoriasis and its clinical subtypes.

doi:10.1016/j.ajhg.2014.07.002

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Article

Fine mapping major histocompatibility complex associations in psoriasis and its clinical subtypes.

American journal of human genetics - 7 Aug 2014

Okada Yukinori, Han Buhm, Tsoi Lam C, Stuart Philip E, Ellinghaus Eva, Tejasvi Trilokraj, Chandran Vinod, Pellett Fawnda, Pollock Remy, Bowcock Anne M, Krueger Gerald G, Weichenthal Michael, Voorhees John J, Rahman Proton, Gregersen Peter K, Franke Andre, Nair Rajan P, Abecasis Gonçalo R, Gladman Dafna D, Elder James T, de Bakker Paul I W, Raychaudhuri Soumya

Abstract excerpt

Psoriasis vulgaris (PsV) risk is strongly associated with variation within the major histocompatibility complex (MHC) region, but its genetic architecture has yet to be fully elucidated. Here, we conducted a large-scale fine-mapping study of PsV risk in the MHC region in 9,247 PsV-affected individuals and 13,589 controls of European descent by imputing class I and II human leukocyte antigen (HLA) genes from SNP...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25087609
DOI: 10.1016/j.ajhg.2014.07.002
PMCID: PMC4129407

Genes

MICA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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