Article
Using maximal segmental score in genome-wide association studies.
Genetic epidemiology - 1 Sept 2012
Lin Ying-Chao, Hsiao Ching-Lin, Hsieh Ai-Ru, Lian Ie-Bin, Fann Cathy S J
Abstract excerpt
Genome-wide association studies (GWAS) have become the method of choice for identifying disease susceptibility genes in common disease genetics research. Despite successes in these studies, much of the heritability remains unexplained due to lack of power and low resolution. High-density genotyping arrays can now screen more than 5 million genetic markers. As a result, multiple comparison has become an important...
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