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LDMAP: the construction of high-resolution linkage disequilibrium maps of the human genome.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2007

Kuo Tai-Yue, Lau Winston, Collins Andrew R

Abstract excerpt

The precise characterization of the linkage disequilibrium (LD) landscape from high-density single-nucleotide polymorphism (SNP) data underpins the association mapping of diseases and other studies. We describe the algorithm and implementation of a powerful approach for constructing LD genetic maps with meaningful map distances. The computational problems posed by the enormous number of SNPs typed in the HapMap...

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PMID: 17984537
DOI: 10.1007/978-1-59745-389-9_4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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