Article
Pairwise shared genomic segment analysis in three Utah high-risk breast cancer pedigrees.
BMC genomics - 28 Nov 2012
Cai Zheng, Thomas Alun, Teerlink Craig, Farnham James M, Cannon-Albright Lisa A, Camp Nicola J
Abstract excerpt
BACKGROUND: We applied a new weighted pairwise shared genomic segment (pSGS) analysis for susceptibility gene localization to high-density genomewide SNP data in three extended high-risk breast cancer pedigrees. RESULTS: Using this method, four genomewide suggestive regions were identified on chromosomes 2, 4, 7 and 8, and a borderline suggestive region on chromosome 14. Seven additional regions with at least...
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