Article
Detecting local high-scoring segments: a first-stage approach for genome-wide association studies.
Statistical applications in genetics and molecular biology - 1 Jan 2006
Guedj Mickael, Robelin David, Hoebeke Mark, Lamarine Marc, Wojcik Jérôme, Nuel Gregory
Abstract excerpt
Genetic epidemiology aims at identifying biological mechanisms responsible for human diseases. Genome-wide association studies, made possible by recent improvements in genotyping technologies, are now promisingly investigated. In these studies, common first-stage strategies focus on marginal effe...
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