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Article

Identification of regions of positive selection using Shared Genomic Segment analysis.

European journal of human genetics : EJHG - 1 Jun 2011

Cai Zheng, Camp Nicola J, Cannon-Albright Lisa, Thomas Alun

Abstract excerpt

We applied a shared genomic segment (SGS) analysis, incorporating an error model, to identify complete, or near complete, selective sweeps in the HapMap phase II data sets. This method is based on detecting heterozygous sharing across all individuals within a population, to identify regions of sharing with at least one allele in common. We identified multiple interesting regions, many of which are concordant with...

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Identifiers

PMID: 21304558
DOI: 10.1038/ejhg.2010.257
PMCID: PMC3110045

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