Article
Pairing of homologous regions in the mouse genome is associated with transcription but not imprinting status.
PloS one - 1 Jan 2012
Krueger Christel, King Michelle R, Krueger Felix, Branco Miguel R, Osborne Cameron S, Niakan Kathy K, Higgins Michael J, Reik Wolf
Abstract excerpt
Although somatic homologous pairing is common in Drosophila it is not generally observed in mammalian cells. However, a number of regions have recently been shown to come into close proximity with their homologous allele, and it has been proposed that pairing might be involved in the establishment or maintenance of monoallelic expression. Here, we investigate the pairing properties of various imprinted and...
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